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—We thank Dr Burde for his interest in our study. We agree that many investigators have made the important observation that an afferent pupillary defect may be found in asymmetric glaucoma. Our study sought to take this clinical finding a step further. We attempted to correlate the depth of the afferent pupillary defect, as measured by neutral-density filters, with a quantitative assessment of the degree of asymmetric visual field loss and disc damage. We also compared patients with asymmetric glaucoma with and without an afferent pupillary defect and found that the afferent pupillary defect developed only after a certain threshold of asymmetric damage had been exceeded.
Brown RH, Zilis JD, Lynch MG, Sanborn GE. Afferent Pupillary Defect in Asymmetric Glaucoma-Reply. Arch Ophthalmol. 1988;106(6):721. doi:10.1001/archopht.1988.01060130791010
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