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November 1988

Branhamella Keratitis Resistant to Penicillin and Cephalosporins

Arch Ophthalmol. 1988;106(11):1506-1507. doi:10.1001/archopht.1988.01060140674014

To the Editor.  Branhamella catarrhalis, a gram-negative diplococcus, is generally considered to be nonpathogenic. To date, only ten cases of keratitis caused by this organism have been reported.1,2 All of these infections proved to be sensitive to penicillin or a first-generation cephalosporin. Herein we report a case of rapidly progressive B catarrhalis keratitis that was resistant to both penicillin and a first-generation and two third-generation cephalosporins.

Report of a Case.  —A 46-year-old debilitated man with a history of chronic alcoholism presented with a six-day history of pain and decreased vision in the right eye. Examination disclosed best corrected visual acuities of light perception in the right eye and 20/30 OS. A bilateral blepharitis was noted. Slit-lamp biomicroscopic examination of the right cornea demonstrated a 4 × 5-mm inferonasal epithelial defect with an underlying stromal infiltrate. No hypopyon was present. The intraocular pressure in the right eye was 28