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January 1989

Application of Minute Amounts of Glue to the Cornea

Arch Ophthalmol. 1989;107(1):15. doi:10.1001/archopht.1989.01070010017003

To the Editor.  —Polycyanoacrylates have been shown to be useful in various corneal diseases, including traumatic perforations and peripheral melting conditions. Many articles discuss its use in already-perforated eyes. However, it is known that glue is a useful adjunct that can aid in corneal healing before perforation occurs.1 It can be difficult, however, to apply very small amounts of glue to a precise location on the cornea. A new method of controlled glue application is presented by illustrating its use in a patient in whom melting of a corneal transplant threatened perforation.

Report of a Case.  —A 40-year-old man with keratoconus and pellucid marginal degeneration underwent corneal transplantation in the left eye. His postoperative course was marked by persistent epithelial defects. He then developed a noninfected 90% loss of stroma at the graft-host interface despite patching and discontinuation of steroid treatment. We elected to glue the area in an