To the Editor.
—I read with great interest Dr Jampol's editorial in the July 1988 issue of the Archives.1 It is reassuring to know that we now have two well-designed studies2,3 that support many ophthalmologists' impression that posterior capsulotomy is associated with a higher incidence of pseudophakic cystoid macular edema (CME). However, it is possible that these studies underestimate the real incidence of postoperative CME because both studies include only patients treated with corticosteroids for the entire duration of the investigation. Therefore, the results reflect not only the effect of a primary posterior capsulotomy on the development of CME but also the effects of concurrent use of corticosteroids and the influence of a posterior capsule on corticosteroid ocular penetration and distribution. Although no well-controlled study has been reported that demonstrates that corticosteroids have any effect on prevention or treatment of CME,4 many ophthalmologists believe they have a
Flach AJ. Cystoid Macular Edema Following Cataract Surgery. Arch Ophthalmol. 1989;107(2):166. doi:10.1001/archopht.1989.01070010172003
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