• Two patients had protracted blind spot enlargement, photopsia, and no optic disc edema. Both had fundus and fluorescein angiographic findings typical of multiple evanescent white dot syndrome that resolved within several weeks, leaving a persistent enlarged blind spot and photopsia. These clinical findings and an analysis of the literature data suggest that acute idiopathic blind spot enlargement without optic disc edema may be a subset of multiple evanescent white dot syndrome.