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April 1989

Follicular Thyroid Cancer Metastatic to the Iris

Author Affiliations


Arch Ophthalmol. 1989;107(4):494-495. doi:10.1001/archopht.1989.01070010508015

To the Editor.  —Metastatic lesions to the anterior segment are rare, and usually secondary to carcinomas of the lung or breast. We report the first case, to our knowledge, of iris metastasis from a mixed papillary follicular thyroid carcinoma. Diagnosis and treatment of this unusual lesion was performed noninvasively using radioactive iodine specific for follicular thyroid carcinoma.

Report of a Case.  —An 82-year-old man known to have metastatic mixed papillary follicular thyroid carcinoma presented with decreased vision and intermittent ocular pain of the left eye. Slit-lamp examination revealed a 5 × 2-mm pink vascularized mass in the iris. Gonioscopy showed the lesion was juxtaposed to the angle without infiltrating the angle structure or peripheral anterior synechiae. The lens showed 1+ nuclear sclerosis in both eyes. No cells or flare were present in the anterior chamber and the intraocular pressure was 14 mm Hg. After dilatation, an anterior chamber reaction developed

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