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July 1989

Ocular Manifestations in Pediatric Patients With Acquired Immunodeficiency Syndrome

Author Affiliations

From the Department of Ophthalmology, Bascom Palmer Eye Institute (Drs Dennehy, Warman, and Flynn), and the Department of Pediatrics (Drs Scott and Mastrucci), University of Miami (Fla) School of Medicine. Dr Dennehy is now with Henry Ford Hospital, Detroit, Mich.

Arch Ophthalmol. 1989;107(7):978-982. doi:10.1001/archopht.1989.01070020040025

• Forty pediatric patients seropositive for human immunodeficiency virus antibody and conforming to Centers for Disease Control, Atlanta, Ga, case definition of acquired immunodeficiency syndrome underwent ophthalmic examinations to evaluate prospectively the incidence, type, and natural history of ocular involvement in pediatric acquired immunodeficiency syndrome. A total of 87 examinations were performed on the patient population throughout the course of the study. Twenty percent had ocular findings, including two cases of cytomegalovirus retinitis, one case of isolated retinal cotton-wool spots, one case of toxoplasmosis retinochoroiditis, and three cases of external infections of adnexal structures. One patient had unusual peripheral retinal findings. The incidence of ocular manifestations in pediatric acquired immunodeficiency syndrome is considerably less than reported in several adult series. However, we recommend ophthalmic screening in all pediatric patients with acquired immunodeficiency syndrome with encephalopathy or disseminated opportunistic infections, or when symptoms suggest ophthalmic involvement.

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