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November 1989

The Effect of Anterior Chamber Depth on Endothelial Cell Count After Filtration Surgery

Author Affiliations

From the Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Mass, and Ophthalmic Consultants of Boston Inc.

Arch Ophthalmol. 1989;107(11):1609-1611. doi:10.1001/archopht.1989.01070020687028

• Eighteen patients undergoing glaucoma filtration surgery underwent specular microscopic examination 1 day prior to surgery and 4 to 6 months after surgery. Patients were evaluated postoperatively for the presence of iridocorneal or lenticular-corneal touch, anterior chamber depth, and inflammation. Ten eyes that maintained their anterior chamber following glaucoma filtration surgery did not have a significant decrease in corneal edothelial cell density. However, eight eyes that developed a shallow anterior chamber with iridocorneal touch had a mean (± SD) decrease of 265 ± 185 cells (12.4%) peripherally and 250 ± 243 cells (11.6%) centrally in corneal endothelial cell count. None of the patients with iridocorneal touch developed corneal edema after a mean follow-up of 44.4 ± 18.0 months. Iridocorneal touch after glaucoma filtration surgery is associated with loss of endothelial cells yet appears to be well tolerated by the cornea.

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