• A 55-year-old woman with chronic renal failure treated with hemodialysis had severe bilateral visual loss develop due to retinal ischemia. Ophthalmoscopy showed crystals in the distribution of the retinal arteries, but not veins, and this led to a diagnosis of systemic oxalosis. Factors contributing to systemic oxalosis in addition to renal failure were ascorbic acid dietary supplementation, pyridoxine deficiency, and ileal resection. Histopathologic findings showed ocular calcium oxalate deposition limited nearly entirely to the walls of retinal blood vessels.
Wells CG, Johnson RJ, Qingli L, Bunt-Milam AH, Kalina RE. Retinal Oxalosis: A Clinicopathologic Report. Arch Ophthalmol. 1989;107(11):1638–1643. doi:10.1001/archopht.1989.01070020716035
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.