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March 1990

Trazodone-Induced Palinopsia

Author Affiliations

From the Neuro-opthalmology Unit, Department of Ophthalmology, Harvard Medical School, and the Massachusetts Eye and Ear Infirmary, Boston.

Arch Ophthalmol. 1990;108(3):399-400. doi:10.1001/archopht.1990.01070050097040

• Palinopsia refers to the persistence or reappearance of an image of a recently viewed object. Typically, patients with palinopsia have other visual symptoms or signs, and the underlying cause is a structural lesion of the posterior portions of the cerebral hemispheres. However, we treated three patients who experienced palinopsia as an isolated symptom, apparently as a side effect of trazodone hydrochloride therapy for depression. The palinopsia was dose related and disappeared with reduction or cessation of therapy.

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