• Palinopsia refers to the persistence or reappearance of an image of a recently viewed object. Typically, patients with palinopsia have other visual symptoms or signs, and the underlying cause is a structural lesion of the posterior portions of the cerebral hemispheres. However, we treated three patients who experienced palinopsia as an isolated symptom, apparently as a side effect of trazodone hydrochloride therapy for depression. The palinopsia was dose related and disappeared with reduction or cessation of therapy.
Hughes MS, Lessell S. Trazodone-Induced Palinopsia. Arch Ophthalmol. 1990;108(3):399–400. doi:10.1001/archopht.1990.01070050097040
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