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September 1990

Treatment of Pneumocystis carinii Choroidopathy

Author Affiliations

Chicago, Ill

Arch Ophthalmol. 1990;108(9):1214-1215. doi:10.1001/archopht.1990.01070110030009

Pneumocystis carinii choroidopathy in patients with the acquired immunodeficiency syndrome (AIDS) is a recently recognized clinical entity. The long-term natural history is not well described and the response to antimicrobial therapy has been reported in only a single patient, to our knowledge.1 We followed up a patient with AIDS and bilateral, multifocal Pneumocystis choroidopathy and report herein on the slow regression of all lesions following treatment.

Report of a Case.  —A 22-year-old white woman with a history of heterosexual contact with an intravenous drug abuser developed P carinii pneumonia in July 1988. Serologic testing at that time was positive for human immunodeficiency virus 1 antibodies. The patient was treated successfully with a 3-week course of parenteral pentamidine isethionate since she was found to be allergic to sulfamethoxazole. Subsequently, she received aerosolized pentamidine every other week as suppressive therapy.In June 1989, the patient presented with intermittent blurring of vision