Cytomegalovirus (CMV) retinitis is the most common opportunistic ocular infection of the acquired immunodeficiency syndrome (AIDS). Cytomegalovirus antigens have been immunohistochemically localized in all layers of the retina, but are rarely found in ocular tissue other than the retina.1,2 We recently cared for a patient with AIDS and CMV retinitis who developed endophthalmitis following a scleral buckling procedure. Cytomegalovirus was the only pathogen identified on histopathologic examination of the eye and was present in spindle cells and vascular endothelial cells of the organized vitreous.
Report of a Case.
—A 31-year-old man with AIDS was being treated with intravenous ganciclovir for bilateral CMV retinitis. The patient had been doing well for nearly 3 months, with visual acuities of 20/40 OD and 20/20 OS, when an area of retinal whitening and intraretinal hemorrhage developed in the periphery of the superior temporal retina of the right eye. The dosage of ganciclovir
Margo CE, Pavan PR. Extraretinal Cytomegalovirus Infection Following Retinal Reattachment Surgery in a Patient With Acquired Immunodeficiency Syndrome. Arch Ophthalmol. 1990;108(9):1215–1216. doi:10.1001/archopht.1990.01070110031010
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.