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September 1990

Refractive Predictability of Myopic Hydrogel Intracorneal Lenses in Nonhuman Primate Eyes

Arch Ophthalmol. 1990;108(9):1310-1315. doi:10.1001/archopht.1990.01070110126036

• The refractive predictability of myopic hydrogel intracorneal lenses made of lidofilcon A was evaluated in 24 monkey eyes following a microkeratome dissection. All eyes were examined monthly for refractive alteration and clinical appearance during a follow-up period of 7 to 33 months. The refractive yield was measured by retinoscopy and found to be a function of the implant depth. The mean±SD percent of the desired correction achieved averaged 70%±24% at a 36% to 60% depth (n = 8), 54%±22% at a 61% to 79% depth (n = 7), and 12%±14% in implants deeper than at a 79% depth (n = 9). For eyes with implants at a 36% to 60% depth, the predicted vs achieved refractive alteration yielded a correlation coefficient of.97 (88% within ± 3 diopters of the correlation). The refractive outcome remained stable throughout 7 months of follow-up, whereas deeply placed lenses (≥80%) exhibited significant regression in power during this time.