[Skip to Content]
[Skip to Content Landing]
December 1990

Removal of Radiation-Induced Cataracts in Patients Treated for Retinoblastoma

Author Affiliations

From the Vitreoretinal Service, Tallahassee, Fla (Dr Brooks); the Vitreoretinal Foundation, Memphis, Tenn (Drs Meyer and Balas); the Oncology Service (Dr Shields) and Pediatric Department (Dr Nelson), Wills Eye Hospital, Philadelphia, Pa; and St Jude Children's Research Hospital, Memphis (Dr Fontanesi).

Arch Ophthalmol. 1990;108(12):1701-1708. doi:10.1001/archopht.1990.01070140055028

• Experience with removal of radiation-induced cataract in patients treated for retinoblastoma is limited. We retrospectively reviewed the records of 38 patients with retinoblastoma (42 eyes) who underwent removal of radiation-induced cataract from 1973 to 1989. Nineteen eyes (45%) without macular tumors or severe radiation complications had final visual acuities in the range of 20/20 to 20/50. One eye (2.4%) developed a rhegmatogenous retinal detachment and four eyes (9.5%) were noted to have amblyopia after cataract removal. Three eyes (7%) developed retinoblastoma recurrence, one with extension of retinoblastoma into the subconjunctival space through the previous sclerotomy. Exenteration was performed and the patient was alive after 8 years. Cataract removal can be visually beneficial in selected patients with radiation-induced cataracts.