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January 1991

Endophthalmitis From Contaminated Donor Corneas Following Penetrating Keratoplasty

Author Affiliations

From the King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Arch Ophthalmol. 1991;109(1):54-59. doi:10.1001/archopht.1991.01080010056032

• We encountered six (0.2%) cases of endophthalmitis resulting from contaminated donor corneas between January 1983 and July 1990 following a total of 3000 consecutive penetrating keratoplasties. Causative organisms in the three cases of fungal endophthalmitis were Torulopsis glabrata, Candida albicans, and Aspergillus flavus; the three cases of bacterial endophthalmitis were due to Klebsiella pneumoniae, Staphylococcus aureus, and Enterococcus faecalis. All organisms were resistant to gentamicin in the preservation media. A significantly higher incidence of endophthalmitis was noted in patients receiving corneas from a Sri Lankan eye bank (1.25%) than in those receiving US eye bank tissue (0.14%). Donor rim cultures are important to identify those patients at increased risk of developing endophthalmitis, enabling earlier diagnosis and more specific treatment should endophthalmitis occur.