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March 1991

Adult Vitelliform Macular Degeneration Progressing to Full-Thickness Macular Hole

Author Affiliations

New York, NY

Arch Ophthalmol. 1991;109(3):325. doi:10.1001/archopht.1991.01080030027024

The association of pseudovitelliform or adult vitelliform macular degeneration and full-thickness macular hole has been suggested by the appearance of each lesion in one eye in four elderly individuals.1 We describe a patient who presented with good visual acuity and bilateral vitelliform lesions. During a 4-year period, she developed bilateral, full-thickness macular holes.

Report of a Case.  —An asymptomatic 68-year-old woman was noted to have bilateral, symmetrical, ovoid, deep yellowish lesions in the macula on routine examination. Her history was notable for hypertension, being controlled with therapy, an acute myocardial infarction, and femoral artery bypass surgery.The patient's visual acuity was 20/20 OD and 20/30 OS. The ocular examination results were normal except for the yellow macular lesions. A fluorescein angiogram showed hyperfluorescence of the lesions that occurred early and persisted without leakage in the late stages.One year later, her visual acuity had diminished to 20/100 OS and

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