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April 1991

A History of Immunology

Author Affiliations

Boston, Mass

Arch Ophthalmol. 1991;109(4):479. doi:10.1001/archopht.1991.01080040047021

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In this book Arthur Silverstein undertakes the ambitious task of presenting, in historic context, the unifying themes of immunologic research. He succeeds brilliantly. This is an epistemology of scientific thought, of immunology in particular, and a history of ideas. Rather than follow a time line through developments in the field, Silverstein chooses the more challenging, but also more rewarding, thematic approach. Most chapters focus on a major immunologic concept or problem, its importance in the context of scientific and social thought at various times, the major scientists who theorized on or investigated the concept, and the concept's place in our current paradigm.

Some of the chapters have been published previously, and others were written specifically for this book. Each chapter can be read and appreciated alone, but, when considered as a group, they yield a history of immunologic thought with both detail and scope. The chapters include the following: "Theories

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