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May 1991

Krypton Laser Photocoagulation for Neovascular Lesions of Age-Related Macular Degeneration

Author Affiliations

Baltimore, Md

Arch Ophthalmol. 1991;109(5):614-615. doi:10.1001/archopht.1991.01080050020011

To the Editor.  —The Macular Photocoagulation Study (MPS) Group recently reported the results of a randomized clinical trial comparing krypton red laser photocoagulation with no treatment for choroidal neovascular lesions involving the foveal avascular zone in patients with age-related macular degeneration.1 Although a thorough review of the literature was not the purpose of the report, earlier work by Yassur et al2 had bearing on the MPS results and should have been cited. Their results from a randomized trial involving 123 eyes with age-related macular degeneration and neovascular lesions involving the foveal avascular zone showed that 37 (67% ) of 55 untreated eyes had deterioration in visual acuity in comparison with only 22 (32% ) of 68 eyes treated with krypton laser. The MPS results for similar eyes showed that 98 (58% ) of 169 untreated eyes in comparison with 86 (49% ) of 174 treated eyes had severe visual loss (six or

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