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August 1991

Silicone Intraocular Lens Implant Discoloration in Humans

Author Affiliations

Claremont, Calif

Arch Ophthalmol. 1991;109(8):1057. doi:10.1001/archopht.1991.01080080015001

To the Editor.  —In response to Milauskas' letter1 pertaining to discoloration of certain silicone lenses including some manufactured by IOLAB Corp, Claremont, Calif, IOLAB surveyed all of the IOLAB investigators whose patients underwent intraocular lens (IOL) implantation of lenses manufactured in the same time frame as those reported by Milauskas. None of these investigators identified discoloration of the IOLAB silicone lenses.Ongoing stability tests of intraocular lenses heated to 45°C are being conducted by IOLAB. After 14 months at this temperature, there is no discernible discoloration. This would be equivalent to approximately 2.5 years at the temperature to which the lens is exposed in the eye.We reviewed our material use and process for manufacturing silicone lenses and did not find any changes that might account for a sporadic discoloration among Milauskas' patients.To date, we have seen one patient at Milauskas' office. Using slit-lamp examination, there was an almost

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