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October 1991

Corneal Toxicity Secondary to Hydrogen Peroxide-Saturated Contact Lens

Author Affiliations

Detroit, Mich

Arch Ophthalmol. 1991;109(10):1352. doi:10.1001/archopht.1991.01080100032019

Microfiltered 3% hydrogen peroxide (H2O2) solutions have become increasingly popular as disinfectants for soft contact lenses. We report a case in which an aphakic soft contact lens stored for a week in a 3% H2O2 solution (30 000 ppm) and inserted without neutralization caused a reversible corneal opacity.

Report of a Case.  —An 85-year-old woman without a history of blepharitis or dry eye had undergone a penetrating keratoplasty with an extracapsular cataract extraction and posterior chamber lens implantation in the left eye for Fuchs' corneal dystrophy 8 years earlier. Five months later, she developed a traumatic wound dehiscence requiring intraocular lens removal and anterior vitrectomy, resulting in a final visual acuity of 20/200 OS. Postoperatively, the graft remained clear, with an epithelium that appeared to be normal and a corneal thickness of 0.64 mm. Recently, the patient presented for reinsertion of her aphakic

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