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October 1991

Unilateral Acute Idiopathic Maculopathy

Author Affiliations

From The LuEsther T. Mertz Retinal Research Laboratory, Manhattan Eye, Ear and Throat Hospital (Drs Yannuzzi and Sorenson), The Macula Foundation, Inc (Drs Yannuzzi and Sorenson), and Columbia University School of Medicine (Drs Yannuzzi and Sorenson), New York, NY; Department of Ophthalmology, Northwestern University Medical School, Chicago, Ill (Dr Jampol); Department of Ophthalmology and Visual Sciences, Eye and Ear Infirmary, UIC Eye Center, University of Illinois at Chicago (Dr Rabb); Stony Brook (NY) University (Dr Beyrer); Southside Hospital, Bayshore, NY (Dr Beyrer); Concord (NH) Hospital (Dr Wilcox); Veterans Administration Hospital, Boston, Mass (Dr Wilcox); and Cornell University Medical College, New York (Dr Wilcox).

Arch Ophthalmol. 1991;109(10):1411-1416. doi:10.1001/archopht.1991.01080100091049

• This is a report of nine patients who experienced sudden, severe, unilateral central vision loss following a flulike illness. Each patient had an exudative detachment of the macula. All patients experienced a spontaneous resolution of the acute macular manifestations with near-complete recovery of vision. A characteristic "bull's-eye" appearance in the macula persisted. The acute manifestations of the disorder did not recur in any of the patients during the period of follow-up. The constellation of findings was suggestive of an inflammatory disease of the retinal pigment epithelium, but a specific causative agent could not be identified. The acute clinical and angiographic features, the natural course, and the residual pigment epithelial derangement were not consistent with any previously described disorder.

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