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November 1991

Discoloration of a Silicone Intraocular Lens 6 Weeks After Surgery-Reply

Author Affiliations

Palm Springs, Calif

Arch Ophthalmol. 1991;109(11):1494. doi:10.1001/archopht.1991.01080110028014

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In Reply.  —The communication from Dr Watt is extremely timely and significant; he must be congratulated on his clinical finding of a discolored silicone IOL 6 weeks after surgery. Dr Watt's report is also significant because it now demonstrates that the behavior of "silicone" as an IOL material in the human eye is not isolated to the two manufacturers originally reported by me in the Archives, but also involves another major manufacturer of silicone IOLs. In a recent Ocular Surgery News teleconference on discolored silicone IOLs, Patricia Knight, PhD, of Allergan Medical Optics, Irvine, Calif, confirmed that there were reports of 1% hazing or discoloring of some IOLs in early clinical studies and 0.7% discoloration in later studies. I believe that some silicone IOLs can discolor very early after implantation. The discoloration of the silicone IOL occurring within 6 weeks of implantation does not surprise me, because a retrospective examination

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