To the Editor.
—Welding, or fusion, of tissues using laser energy was first described by Jain and Gorisch.1,2 The process involves some heat rise and apparently involves dissociation and reassociation of collagen fibrils without causing complete protein denaturation. Attempts to weld corneal or other ocular tissues have not met with success to date.3,4We report the fusion of corneal stroma in porcine cadaver eyes using two special wavelengths of the laser. The fusion occurred without the use of adhesional or accessory proteins and exhibited mechanical strength dependent on the depth of the fusion. Scleral tissue was also welded, although without the high degree of strength demonstrated by a corneal weld. To our knowledge, this is the first report of welding in corneal or scleral tissue in which significant mechanical strength was exhibited.Porcine eyes were obtained within 6 hours of slaughter. Epithelium was débrided by scraping it with
Burstein NL, Williams JM, Nowicki MJ, Johnson DE, Jeffers WQ. Corneal Welding Using Hydrogen Fluoride Lasers. Arch Ophthalmol. 1992;110(1):12–13. doi:10.1001/archopht.1992.01080130014004