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January 1992

Excimer Laser Ablation of Infectious Crystalline Keratopathy

Author Affiliations

Louisville, Ky

Arch Ophthalmol. 1992;110(1):18. doi:10.1001/archopht.1992.01080130020011

Infectious crystalline keratopathy is an uncommon infection caused by a variety of streptococci.1 We report herein the successful use of the excimer laser to eradicate a case of intractable disease.

Report of a Case.  —A 68-year-old white woman wore extended-wear contact lenses for correction of aphakia. She developed fernlike opacities in the anterior stroma without evidence of ocular inflammation (Fig 1). Cultures and scrapings revealed no growth and a presumptive diagnosis of infectious crystalline keratopathy was made. The patient was administered topical vancomycin hydrochloride without any clinical response. Because of the superficial location of the lesions, we attempted to eradicate her infection with the excimer laser under a Phase II-B protocol that has been approved by the Food and Drug Administration.A peribulbar block was administered using 4% Xylocaine (lidocaine), and the patient was aligned under a 193-nm argon fluoride excimer laser (Taunton LV 2000, Taunton Technologies, Monroe, Conn).

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