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February 1992

The Formation of Moisture Droplets on the Posterior Surface of Intraocular Lenses During Fluid/Gas Exchange Procedures

Arch Ophthalmol. 1992;110(2):168. doi:10.1001/archopht.1992.01080140018003

To the Editor.  —The formation of droplets of moisture on the posterior surface of silicone intraocular lenses (IOLs) during fluid/air exchange has been reported. The obvious concern regarding this phenomenon is the possibility that intraoperative viewing of the fundus could be impaired. The proposed mechanism for the phenomenon was moist air in the eye condensing on the IOL, which had been previously chilled by the infusion fluid used during vitrectomy.1We are investigating this phenomenon on silicone and polymethyl methacrylate IOLs (S1-18NB and PC-15B, respectively, Allergan Medical Optics, Irvine, Calif) implanted in rabbit eyes. Our operative procedure consists of a fluid/air exchange after vitrectomy, with observation of droplet formation using a quantitative grading system. Preliminary results demonstrate that droplets form on both lenses only when the posterior capsule is opened. Droplet formation is more pronounced with silicone lenses but has been cleared in all cases with the application of