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February 1992

Clinical Comparison of Grafts Stored in McCarey-Kaufman Medium at 4°C and in Corneal Organ Culture at 31°C

Author Affiliations

From the Cornea Service, Rotterdam (the Netherlands) Eye Hospital (Drs Rijneveld and Beekhuis and Ms Rinkel-van Driel); the Department of Ophthalmology, University of Groningen (the Netherlands) (Dr van Rij); and the Netherlands Ophthalmic Research Institute, Amsterdam (Dr Pels).

Arch Ophthalmol. 1992;110(2):203-205. doi:10.1001/archopht.1992.01080140059027

• Twenty-eight paired human corneas were preserved in minimal essential medium at 31°C and in McCarey-Kaufman medium at 4°C. These grafts were then transplanted in pairs of patients with keratoconus who were age matched as closely as possible. These pairs received donor corneas from the same donor, so for each pair the donor age and time from death to preservation were the same. Visual acuity, central corneal thickness, and endothelial cell counts were compared. During the 1- to 2-year study period, no statistically significant difference in visual acuity, corneal thickness, or endothelial cell density was found between grafts stored in minimal essential medium and those stored in McCarey-Kaufman medium.