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August 1992

Effect of Continuous Circular Capsulorhexis and Intraocular Lens Fixation on the Blood-Aqueous Barrier

Author Affiliations

From the Institute of Ophthalmology, Tane Memorial Eye Hospital (Drs Tsuboi, Tsujioka, and Kojima) and the Department of Ophthalmology, Kinki University School of Medicine (Dr Kusube), Osaka, Japan.

Arch Ophthalmol. 1992;110(8):1124-1127. doi:10.1001/archopht.1992.01080200104035

• Permeability across the bloodaqueous barrier to fluorescein was estimated fluorophotometrically in pseudophakic eyes for which a continuous circular capsulorhexis was performed. The permeability index was significantly higher in the in-the-bag fixations than in the out-of-the-bag fixations at 3 and 6 months after surgery, when only bilateral cases were enrolled. Damage to the barrier in eyes with the in-the-bag fixations was attributable to the broad attachment of optics to the anterior capsule, because a positive linear regression was obtained between the permeability index and the doughnut-shaped contact area in eyes with the in-the-bag fixations. The permeability index in eyes with the in-the-bag fixations was as low as that in eyes with the out-of-the-bag fixations when the contact area was small. These results indicate an unfavorable effect of the in-the-bag fixation with broad contact of the optics with the anterior capsule and, thus, suggest either an in-the-bag fixation with a large capsulorhexis or an out-of-the-bag fixation.

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