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October 1992

Ocular Histopathology: A Guide to Differential Diagnosis

Author Affiliations

Philadelphia, Pa

Arch Ophthalmol. 1992;110(10):1376. doi:10.1001/archopht.1992.01080220038014

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


In this small volume, the authors present a new and highly effective approach to the teaching of ocular histopathology. Rather than an encyclopedic compendium, they have given readers a series of diagnostic problems and have urged them to approach each diagnosis as a pathologist would. The morphologic changes are presented first. From these changes, a descriptive diagnosis is developed that can then be used as a starting point in the differential diagnosis. These deliberations, together with the clinical history, are used to make a final diagnosis.

The authors have selected 52 cases, each one carefully chosen to emphasize a descriptive conclusion that they call a "pivot diagnosis." Each pivot diagnosis is used as the basis for comparison with groups of diseases that share certain morphologic features. Elements of the pivot diagnosis are described in the text and shown in accompanying photomicrographs. Differential diagnostic possibilities are listed and discussed in detail,

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