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February 1993

Paralysis of Downgaze in Two Patients With Clinical-Radiologic Correlation

Author Affiliations

From the Department of Ophthalmology (Drs Green and Newman), Neurology (Dr Newman), and Neurosurgery (Dr Newman), Emory University School of Medicine, Atlanta, Ga, and the Department of Ophthalmology, North Shore University Hospital-Cornell University Medical College, Manhasset, NY (Dr Winterkorn).

Arch Ophthalmol. 1993;111(2):219-222. doi:10.1001/archopht.1993.01090020073026

• Selective downgaze paralysis was correlated with discrete bilateral lesions at the mesencephalic-diencephalic junction in a 9-year-old girl following severe pneumococcal meningitis, and in a 64-year-old man who suffered an embolic infarction. Magnetic resonance imaging demonstrated bilateral lesions in the region of the rostral interstitial nucleus of the medial longitudinal fasciculus. Clinical-radiologic correlation allowed identification of the likely vascular cause in both patients.

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