Recent reports have documented the efficacy of tissue plasminogen activator in promoting fistula reformation following trabeculectomy1,2 and relieving fibrin-induced pupillary block after retinal procedures.3 We present herein a case in which we successfully used intracameral tissue plasminogen activator in a diabetic patient with neovascular glaucoma who developed a severe anterior chamber fibrin reaction following trabeculectomy with adjunctive mitomycin C.
Report of a Case.
—A 40-year-old black woman with moderate background diabetic retinopathy underwent an uncomplicated cataract extraction using phacoemulsification with implantation of a posterior chamber intraocular lens in the right eye. The postoperative visual acuity was 20/20. Four months after surgery the patient presented with rubeosis iridis, a 5% hyphema, and counting fingers visual acuity. Immediate panretinal photocoagulation was performed.The patient remained in stable condition until 10 months later when she presented with a Serratia marcescens corneal ulcer and hypopyon in the right eye for which she