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January 1994

Phototherapeutic Keratectomy in Recurrent Corneal Intraepithelial Dysplasia

Author Affiliations

Amberg, Germany; Groningen, the Netherlands; Heroldsberg, Germany

Arch Ophthalmol. 1994;112(1):22-23. doi:10.1001/archopht.1994.01090130032007

The argon-fluoride excimer laser has gained a lot of interest as a treatment modality for superficial ocular abnormalities. We report a case of recurrent corneal intraepithelial dysplasia treated with phototherapeutic keratectomy.

Report of a Case.  A conjunctival squamous cell carcinoma with corneal involvement developed in the right eye of a 65-year-old woman. Because of a recurrence 4 months after epithelial abrasion, penetrating keratoplasty was performed in April 1988 in another clinic. The margins of the excised cornea were free of dysplastic epithelial cells. However, the neoplasia recurred on the corneal graft after a 3-month interval. Each recurrence was treated with abrasion followed by histologic examination, which time and again showed an intraepithelial dysplasia, stage III.In November 1989, slit-lamp microscopy of the right eye showed a superficial dot-shaped epitheliopathic lesion on the nasal half of the corneal graft, paracentral midstromal scars, and peripheral superficial vascularization (Figure 1). On examination, visual

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