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April 1994

Should We Recommend Vitreous Surgery for Patients With Choroidal Neovascularization?

Author Affiliations

Baltimore, Md

Arch Ophthalmol. 1994;112(4):459-461. doi:10.1001/archopht.1994.01090160035017

THE SEQUELAE of choroidal neovascularization (CNV) are important causes of visual morbidity. Age-related macular degeneration (AMD) is the leading cause of visual loss in older Americans. Approximately 90% of blindness secondary to AMD is related to the neovascular type of AMD. Neovascular complications of the ocular histoplasmosis syndrome (OHS) can be an important cause of blindness in younger Americans, especially if untreated.

Laser treatment, as demonstrated in clinical trials by the Macular Photocoagulation Study (MPS) Group, shows a very strong treatment benefit with respect to decreasing the risk of severe visual acuity loss in patients with extrafoveal or juxtafoveal CNV complicating AMD1,2 or OHS,3,4 as well as in patients with new (no prior treatment) subfoveal or recurrent subfoveal CNV complicating AMD.5,6 Patients can expect to preserve good visual acuity (20/40 or better) following laser treatment in more than 85% of extrafoveal cases secondary to OHS. However, virtually

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