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May 1994

Band Keratopathy Secondary to Herpes Simplex or Topical Corticosteroid?

Author Affiliations

Chicago, Ill

Arch Ophthalmol. 1994;112(5):578. doi:10.1001/archopht.1994.01090170022006

I wish to make the following comments with regard to the article by Brik and associates1 in the April 1993 issue of the Archives.

The rapid development of what can be characterized as band keratopathy in the two patients described in their report was previously noted under other circumstances, particularly in patients with severely dry eyes.2 Recently, a number of similar cases were reported at the annual meeting of the Eye Bank Association of America, abstracts of which were published.3 An article in the Archives further illustrated this problem.4 The patients described developed corneal calcification in association with steroidphosphate preparations, particularly when used in the treatment of herpetic keratitis. I treated a patient with herpes zoster with prednisolone phosphate who rapidly developed a calcific cornea severe enough to require a penetrating keratoplasty. It has been suggested that phosphate precipitation may be responsible for this phenomenon. It

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