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July 1994

Nocardial Endophthalmitis

Author Affiliations

Madurai, India

Arch Ophthalmol. 1994;112(7):871-872. doi:10.1001/archopht.1994.01090190013004

We read the article by Zimmerman and colleagues1 titled "Chronic Nocardia asteroides Endophthalmitis After Extracapsular Cataract Extraction" and found it to be interesting. Unlike western countries, in India, nocardial infections of the eye are not rare. In a 2-year period, we reported eight cases of nocardial endophthalmitis following posterior chamber intraocular lens implantation. In all of these cases, infections started within 4 to 18 days after surgery (Figure). All of the eyes responded to topical antibiotic therapy. We used 10% ampicillin sodium, 0.2% trimethoprim sulfate, 30% sulfacetamide sodium, 0.3% norfloxacin, and 0.3% ciprofloxacin hydrochloride, according to the sensitivity of the isolates. In our experience, quinolones were found to be more effective than other drugs. None of the eyes were excised. Globes were restored, with a final visual acuity of light perception or counting fingers. In contrast to the published reports, the posterior chamber was not involved in any of

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