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August 1994

Bacterial Growth Is Significantly Enhanced on Foldable Intraocular Lenses

Author Affiliations

Bonn, Germany

Arch Ophthalmol. 1994;112(8):1015-1016. doi:10.1001/archopht.1994.01090200017002

Bacterial endophthalmitis is a severe but rare postoperative complication of cataract surgery with implantation of an intraocular lens (IOL).1 Recent epidemiologic data have shown that IOLs with polypropylene (Prolene) haptics are associated with a significantly higher risk for postoperative endophthalmitis than all—polymethyl methacrylate (PMMA) lenses.1 Further experimental work by the same authors has shown in vitro preferential adherence of coagulase-negative staphylococci to polypropylene haptics in comparison with PMMA haptics.2 With the development of foldable IOLs for smallincision cataract surgery, new materials (eg, silicone and hydrogel) other than PMMA have been used to manufacture IOLs.

To quantify bacterial growth on the surface of IOLs of various materials, commercially available silicone, hydrogel, and PMMA IOLs were tested. Two IOLs for each type of material were suspended in 500 mL of a peptone culture of coagulase-negative staphylococci at its maximal growth concentration. Five cultures were done (a total of 10

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