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Anatomy, Physiology, and Clinical Applications is an extraordinary scientific masterpiece. The book represents Dr Irene Loewenfeld's lifelong love of and dedication to the understanding of the iris aperture and its mysteries. It will remain unchallenged as the ultimate answer to debates about the pupil for many decades to come.The two-volume set consists of the text in the 1590-page volume I (weight, 4.5 kg), accompanied by the 630-page volume II, which contains the bibliography (more than 14 000 citations!) and index. The preface poignantly relates the travels of Dr Otto Lowenstein, initially the author's mentor and later her collaborator until his death in 1965, from Europe in the ominous 1930s to the United States, and his somewhat fortuitous hiring of a bright, eager young woman to work in his laboratory. The weaving of political, historical, and social threads into the scientific fabric of the story of the pupil
Appen RE. The Pupil: Anatomy, Physiology, and Clinical Applications, Volumes 1 and 2. Arch Ophthalmol. 1994;112(12):1517. doi:10.1001/archopht.1994.01090240023013
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