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May 1995

Does the Melanin Content of Uveal Malignant Melanomas Correlate With Their Magnetic Resonance Imaging Appearance?-Reply

Author Affiliations

Philadelphia, Pa

Arch Ophthalmol. 1995;113(5):556. doi:10.1001/archopht.1995.01100050017012

In reply  We acknowledge Drs Ferris and Bloom for their comments on our article.1 The characteristic appearance of uveal melanoma as hyperintense on T1-weighted images and hypointense on T2-weighted images has been reported to occur in 75% to 95% of cases.1-3 In these reports, the 121 uveal melanomas were evaluated at 1.5 T. It is important to realize that the 11 cases reported in Bloom et al's series4 were evaluated at 0.5 T. Therefore, some caution should be advised when interpreting the experience of Bloom and associates regarding the disparate appearance of uveal melanoma and their statement that only 20% of uveal melanomas demonstrated "characteristic" hyperintensity on T1-weighted images and hypointensity on T2-weighted images at 0.5 T.We agree with Ferris and coworkers5 that there was no statistical correlation between tumor signal intensity and the degree of tumor

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