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July 1995

Cutaneous Melanoma-Associated Retinopathy With Retinal Periphlebitis

Author Affiliations

Boston, Mass
Seattle, Wash

Arch Ophthalmol. 1995;113(7):854-855. doi:10.1001/archopht.1995.01100070024015

Melanoma-associated retinopathy (MAR) is a visual paraneoplastic syndrome occurring in some patients with metastatic cutaneous malignant melanoma. These patients present with a sudden onset of night blindness; the electroretinograms (ERGs) resemble congenital stationary night blindness with myopia1; and their sera produce heavy immunostaining of the rod bipolar cells in the retina.2 We describe a patient with MAR who also had an unusual angiographic finding of retinal periphlebitis that mimicked retinal vasculitis.

Report of a Case.  A 52-year-old white man was examined on April 28, 1993, because of decreased visual acuity in both eyes of 2 months' duration and decreased night vision for 2 weeks. He had no history of night blindness or other visual or ocular problems, and there was no family history of night blindness or retinal degeneration. Metastatic cutaneous malignant melanoma of the back had been diagnosed in November 1990 and during the subsequent 2 years

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