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November 1995

The Use of Silicone Oil for HIV-Related Retinal Detachment

Author Affiliations

Stanford, Calif

Arch Ophthalmol. 1995;113(11):1366-1368. doi:10.1001/archopht.1995.01100110026017

Retinal detachment secondary to cytomegalovirus (CMV) and other herpesviruses in patients with human immunodeficiency virus (HIV) infection represents a unique challenge to the vitreoretinal surgeon. Instead of merely choosing a procedure that is likely to be successful over the long term, the physician must consider a broader range of issues specific to a critically ill patient with multiple systemic infections (some transmissible) whose life expectancy is currently measured in months, rather than years or decades. Cytomegalovirus has long been known to be a part of the nosocomial flora of humankind, but, ironically, it was the era of modern organ transplantation and associated therapeutic immunosuppression that led to its identification as a serious visual pathogen.1 Retinal detachment complicating opportunistic viral retinitis was poorly treatable but, fortunately, rarely encountered,2 owing in part to the small number of patients at risk, the ability to pharmacologically modulate immunosuppression in patients with organ

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