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March 1996

Microscopic Polyangiitis With Ocular Involvement

Author Affiliations

From the Departments of Ophthalmology (Drs Caster, Shetlar, and Yee) and Pathology (Dr Pappolla), the Hermann Eye Center, The University of Texas—Houston Health Science Center.

Arch Ophthalmol. 1996;114(3):346-348. doi:10.1001/archopht.1996.01100130342023

Microscopic polyangiitis is an exclusively small-vessel (arterioles, capillaries, or venules) vasculitis that primarily involves the kidney and often involves the lungs, skin, or nervous system. Characteristic features include focal segmental glomerulonephritis, nongranulomatous necrotizing vasculitis, and serum positive for perinuclear-staining antineutrophil cytoplasmic antibodies (P-ANCA). We report a case of microscopic polyangiitis with previously unreported eyelid and conjunctival manifestations that responded well to immunosuppressive therapy.

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