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June 1996

Neonatal Hepatoblastoma Metastatic to the Choroid and Iris

Author Affiliations

From the Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston (Drs Endo and Walton), and the Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison (Dr Albert).

Arch Ophthalmol. 1996;114(6):757-761. doi:10.1001/archopht.1996.01100130749023

A newborn boy was diagnosed with hepatoblastoma after a systemic workup was prompted because of abnormal-appearing eyes. Radiological examination revealed mass lesions involving the liver, brain, eyes, and ribs. A liver biopsy was performed before death and results showed hepatoblastoma, an unusual solid tumor of childhood. At autopsy, hepatoblastoma was also found histopathologically in the irides and choroid of both eyes. No previous report of hepatoblastoma metastatic to the eye could be found in the medical literature. In addition, we believe this is the first report in a child of a solid tumor metastatic to the choroid and iris, and of a solid tumor metastatic to the iris that is confirmed histopathologically.

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