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July 1996

Endogenous Bacterial Endophthalmitis as a Complication of Intravenous Therapy for Cytomegalovirus Retinopathy

Author Affiliations

Los Angeles, Calif

Arch Ophthalmol. 1996;114(7):879-880. doi:10.1001/archopht.1996.01100140093019

Sepsis is a well-established complication of long-term use of an indwelling catheter. We report a case of endogenous bacterial endophthalmitis that occurred as 1 manifestation of disseminated bacterial infection in a patient receiving daily intravenous (IV) infusions of ganciclovir sodium for the treatment of acquired immunodeficiency syndrome (AIDS)-related cytomegalovirus (CMV) retinopathy. The features were atypical, making diagnosis difficult.

Report of a Case.  A 37-year-old woman who had AIDS and bilateral CMV retinopathy had been receiving IV ganciclovir for 3 months. Her visual acuity was 20/20 OU. The lesions were inactive. The posterior border of the lesion in the right eye extended to the papillomacular bundle.Fever, anorexia, and weight loss developed in the patient 1 month later. Mycobacterium avium complex was isolated from blood cultures. Symptoms persisted despite treatment with clarithromycin and ethambutol hydrochloride. Two weeks later, a purulent discharge was noted at the indwelling catheter tip, and Staphylococcus aureus

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