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May 1997

Lymphocytic Choriomeningitis Virus: A New Addition to the TORCH Evaluation

Author Affiliations

Chicago, Ill

Arch Ophthalmol. 1997;115(5):680-681. doi:10.1001/archopht.1997.01100150682027

Lymphocytic choriomeningitis virus (LCMV), an arenavirus endemic in mice and also reported in hamsters, is occasionally transmitted to humans. Postnatal LCMV results in asymptomatic seroconversion or aseptic meningitis. Intrauterine infection has resulted in spontaneous abortion, as well as congenital hydrocephalus, chorioretinitis, and psychomotor retardation in liveborn infants. This potentially preventable cause of congenital chorioretinitis has only recently been reported in the United States.1-3 We report a case of this clinical entity that, to our knowledge, has hitherto been undescribed in the ophthalmology literature.

Report of a Case.  A 22-month-old girl was referred to the pediatric ophthalmology clinic for evaluation of marked visual delay. She was a 2567-g product of a 37-week gestation. The patient was institutionalized since birth; no history of prenatal complications or infectious exposures was noted. At birth, an ultrasound scan of the head indicated hydrocephalus requiring placement of a ventriculoperitoneal shunt at 5 days of

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