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May 1997

Corneal Sensitivity Debate-Reply

Author Affiliations

Los Angeles, Calif

Arch Ophthalmol. 1997;115(5):686. doi:10.1001/archopht.1997.01100150688032

In reply  We thank Villain et al for their helpful comments. Indeed, our literature search did not turn up 2 of the referenced articles. Nevertheless, in our study we did not report on baseline sensitivities but emphasized the different amounts of decrease in corneal sensitivity in white and nonwhite subjects after repeated instillation of either ketorolac or diclofenac.1 Because this observation had not been expected at the time of the study design, it has to be considered as a preliminary by-product. Therefore, the number of subjects in this study is too small to statistically analyze these results again for iris color. We agree that in further clinical studies focusing on corneal esthesiometry, more volunteers of different ethnic origins should be matched according to their iris color.In their review on corneal hypoesthesia, Martin and Safran2 reported on the results of Millodot,3 which indicated that the corneas of

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