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Case Reports and Small Case Series
February 1999

Scedosporium apiospermum of the Orbit

Arch Ophthalmol. 1999;117(2):268-269. doi:

Scedosporium apiospermum is an emerging fungal pathogen commonly found in soil (even in hospital potted plants1) and polluted water. Ocular infection can occur including keratitis, conjunctival mycetome, endophthalmitis, and panophthalmitis. Reports of orbital involvement have been rare. We describe a 68-year-old man with leukemia who developed an orbital subperiosteal abcess from extension of contiguous fungal pansinusitis. We also review the role of pharmacotherapeutics in the management of this disease. Remarkably, this patient defervesced on antifungal therapy without aggressive surgical debridement.

A 68-year-old man with an 8-month history of acute lymphotogenous leukemia was seen in consultation for the hematology service. He complained of a red, protruding left eye and progressive diplopia over 3 days. He had been admitted to the hospital with neutropenic fevers 5 days earlier.