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Author Affiliations: Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Optical coherence tomography (OCT) has been developed to objectively evaluate structural damage in vivo. The tool can be used to evaluate damage to the circumpapillary retinal nerve fiber layer (cpRNFL). Measurements of the cpRNFL play an important role in the diagnosis and management of patients with glaucoma. The recent introduction of spectral-domain OCT has enhanced the scan resolution and provides more reproducibility for image acquisition compared with time-domain OCT, a previous version of OCT. Furthermore, the RTVue (Optovue Inc), one of the spectral-domain OCT instruments, allows us to evaluate inner retinal layer thickness. Reference to the ganglion cell complex (GCC) includes the retinal nerve fiber layer, retinal ganglion cell layer, and inner plexiform layer. Some studies have demonstrated the usefulness of GCC as well as cpRNFL thickness as measured by RTVue in treating glaucomatous eyes.
Kanamori A, Nakamura M, Yamada Y, Negi A. Longitudinal Study of Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex in Traumatic Optic Neuropathy. Arch Ophthalmol. 2012;130(8):1067–1069. doi:10.1001/archophthalmol.2012.470
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