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Kadonosono K, Yamane S, Arakawa A, et al. Endovascular Cannulation With a Microneedle for Central Retinal Vein Occlusion. JAMA Ophthalmol. 2013;131(6):783–786. doi:10.1001/jamaophthalmol.2013.2585
Author Affiliations: Departments of Ophthalmology (Drs Kadonosono, Yamane, Arakawa, and Inoue) and Endocrinology (Dr Yamakawa), Yokohama City University Medical Center, Yokohama City, Department of Ophthalmology, Fukuoka University Medical School, Fukuoka City (Dr Uchio), and Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo (Drs Yanagi and Amano), Japan.
We developed a new surgical treatment in which a microneedle is used for retinal endovascular cannulation to treat eyes with central retinal vein occlusion by flushing thrombus out of the central retinal vein as it passes through the lamina cribrosa. The eyes of 12 consecutive patients (12 eyes) with central retinal vein occlusion were successfully treated using this novel treatment. At 24 weeks after surgery, 9 of 12 eyes had gained more than 15 letters in best-corrected visual acuity, and the mean decrease in central foveal thickness was 271.1 μm. Few complications were observed. The microneedle is stiff and sharp enough to facilitate retinal endovascular cannulation in eyes with central retinal vein occlusion. This new technique is a promising treatment of macular edema due to central retinal vein occlusion.
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