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Invited Commentary
December 2016

Use of Retinal Optical Coherence Tomography to Detect Congenital Zika Syndrome

Author Affiliations
  • 1New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts
JAMA Ophthalmol. 2016;134(12):1427-1428. doi:10.1001/jamaophthalmol.2016.4299

First identified in rhesus monkeys in Uganda in 1947, the Zika virus (ZIKV), a flavirus spread most commonly by the Aedes aegypti and Aedes albopictus mosquitos,1 was not implicated in human disease until 1953, when it was recognized in Nigeria to produce a mild, febrile illness. The virus, related to the pathogens that cause yellow fever, dengue, and the West Nile virus,1 has emerged recently as a serious health care threat resulting in widespread panic across the globe, particularly in the Pacific and the Americas. The recent outbreak began in Brazil in 2015, with over 1 million people now infected by ZIKV, and has since spread to North and South America, as well as Singapore. Most recently, the Florida Health Department has identified cases in several areas of Miami-Dade country in the United States.2