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Clinicopathologic Report
March 1998

Juvenile Xanthogranuloma of the Iris in an Adult

Author Affiliations

From the Ophthalmology Service, Department of Surgery, Madigan Army Medical Center, Tacoma, Wash.

Arch Ophthalmol. 1998;116(3):377-379. doi:10.1001/archopht.116.3.377

Juvenile xanthogranuloma is a self-limited skin disorder of young children that uncommonly affects the eye. Juvenile xanthogranuloma has been described in adults, but reported intraocular involvement is extremely rare. We report a case of juvenile xanthogranuloma diagnosed in a 25-year-old man who was seen with nontraumatic hyphema and iridocyclitis. Diagnosis was made from a biopsy specimen obtained from a suspicious skin lesion. Topical and systemic steroids, radiation therapy, and finally immunosupression were required to eliminate the iris tumor clinically and resolve the patient's recurrent symptoms.