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Birdshot retinochoroidopathy is a chronic, bilateral uveitic disorder.
Originally described by Ryan and Maumenee,1
it is characterized by posterior segment inflammation in the presence of multiple
depigmented choroidal lesions symmetrically scattered throughout the postequatorial
retina. The cause is presumed to be autoimmune and more than 90% of patients
test positive for the HLA-A29 serotype.2
Approximately half of affected eyes develop cystoid macular edema (CME), and
this represents a major cause of considerable visual loss from this condition.3 A rationale for treatment with corticosteroids
has been established based on the inflammatory nature of the disease. However,
systemic and periocular corticosteroids have failed to produce significant
improvement in most treated patients.4 We
report 2 cases of refractory CME secondary to birdshot retinochoroidopathy
that were successfully treated with intravitreal injections of triamcinolone
Martidis A, Duker JS, Puliafito CA. Intravitreal Triamcinolone for Refractory Cystoid Macular Edema Secondary to Birdshot Retinochoroidopathy. Arch Ophthalmol. 2001;119(9):1380–1383. doi:
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